JANUVIA is a once-daily prescription pill for adults with type 2 diabetes. JANUVIA, along with diet and exercise, helps lower your blood sugar (A1C). Do not take JANUVIA if you are allergic to any of its ingredients, including sitagliptin. If you have any symptoms of a serious allergic reaction, stop taking JANUVIA and call your doctor right away or get emergency medical help. But it can be an early sign of type 2 diabetes, which Januvia is used to treat.
Does Januvia interact with foods or drinks?
And people with kidney problems may need a lower dosage of Januvia. For this reason, be sure your doctor is aware if you have kidney problems before you start taking Januvia. Be sure to talk with your doctor about your health history before you take Januvia. This drug may not be the right treatment for you if you have certain medical conditions or other factors that affect your health. The conditions and factors to consider are described below.
What drugs and food should I avoid while taking Januvia (Sitagliptin)?
If your kidneys aren’t working well, your doctor may adjust your dosage. There aren’t any herbs or supplements that have been specifically reported to interact with Januvia. But some herbs may help reduce the amount of sugar in your blood. Taking these herbs with Januvia may cause hypoglycemia (low blood sugar), which can be dangerous. In addition to helping prevent pregnancy, the hormones in birth control pills can increase the amount of sugar in your blood. With this higher level of sugar in your blood, Januvia may not work as well.
Are there other interactions with Januvia?
These medications are in the same class as Januvia and have similar effects in your body. Januvia works to help keep your blood sugar levels from getting too high. Blocking DPP-4 helps increase the levels of natural hormones in your body called incretins. Incretins help lower blood sugar by increasing insulin levels, especially after meals. They also decrease the amount of glucose (sugar) that is made by the liver.
- Patients who failed to meet specific glycemic goals during the studies were treated with metformin rescue, added on to placebo or JANUVIA.
- Actos use may increase the risk of developing a bladder tumor (mass of tissue), which can be cancerous.
- But sitagliptin, Januvia’s active ingredient, is used in other combination drugs that may cause yeast infections as a side effect.
- They can also include swelling of your tongue, mouth, or throat, which can cause trouble breathing.
- If you have any questions about the safety of Actos, talk with your doctor.
- Call your doctor right away if you have an allergic reaction to Januvia.
Will Januvia stop working to treat my blood sugar after a while?
The most common side effects of JANUVIA are upper respiratory tract infection, stuffy or runny nose and sore throat, and headache. If you have questions about taking this drug, talk with your doctor or pharmacist. They can tell you about other treatments you can use for your condition. Drinking alcoholism rehab alcohol can increase or decrease insulin’s effect. Depending on how much alcohol is consumed, it may have different effects on your blood sugar level. Before taking Januvia, be sure to tell your doctor about all medications you take, including prescription and over-the-counter types.
However, metformin is also approved for use in children ages 10 years and older with type 2 diabetes. Actos works to decrease the amount of sugar in your blood so that you don’t develop complications from diabetes. If you have any questions about ending your Actos treatment, talk with your doctor. If you and your doctor determine that Actos is safe and effective for you, you’ll likely take it long term.
Your pancreas normally makes a hormone called insulin, which takes glucose out of your blood and helps you use the sugar as a source of energy. With type 2 diabetes, your pancreas may not be making enough insulin to remove the sugar from understanding alcohol use disorder national institute your blood. Sometimes your doctor may prescribe Actos along with other medications for your type 2 diabetes, such as glyburide (DiaBeta) or insulin. However, this may put you at risk for developing hypoglycemia (low blood sugar).
Prolonged hemodialysis may be considered if clinically appropriate. It is not known if sitagliptin is dialyzable by peritoneal dialysis. Postmarketing cases of bullous pemphigoid requiring hospitalization have been reported with DPPÂ4 inhibitor use.
They may adjust your diet and exercise routine based on your needs. They may also recommend a dietitian to help make sure you get the proper nutrition. Januvia’s use in people without diabetes who want to lose weight has been studied in one small trial. People in this study had high blood pressure and high cholesterol but did not have diabetes. After taking Januvia for 3 months, they reported reduced body weight.
The most common side effects of JANUVIA include upper respiratory infection, stuffy or runny nose and sore throat, and headache. Clinical data described below suggest that alcohol detox and rehab programs sitagliptin is not susceptible to clinically meaningful interactions by coadministered medications (Table 5). Sitagliptin is not extensively bound to plasma proteins.
Your doctor may also recommend having these tests during your treatment. Based on your test results, your doctor may adjust your Januvia dosage as needed to make sure the drug doesn’t harm your kidneys. If you’ve had heart failure in the past, be sure to tell your doctor before you begin taking Januvia. Severe joint pain typically goes away after stopping treatment with Januvia. You should talk with your doctor before stopping Januvia. In clinical trials, neither weight gain nor weight loss was reported as a side effect of Januvia.
Januvia should help manage your blood sugar for as long as you take it. So while it’s unlikely, it’s possible that your body will stop responding to Januvia after a while. More studies are needed before Januvia can be recommended for weight loss. If you don’t have diabetes and want to lose weight, talk with your doctor.
Off-label use is when a drug that’s approved to treat one condition is used to treat a different condition. Yes, Actos was approved by the Food and Drug Administration (FDA) as safe and effective for the treatment of type 2 diabetes. However, you shouldn’t use Actos if you have type 1 diabetes or diabetic ketoacidosis (a problem that occurs when there’s too much acid in your blood). Never change your dosage of Actos without first talking with your doctor.
They can also include swelling of your tongue, mouth, or throat, which can cause trouble breathing. If you have hypoglycemia, you can safely increase your blood sugar level by eating something that contains sugar. The rule can help get your blood sugar level to a level that’s in the preferred range. To follow this rule, you’ll eat 15 grams (g) of sugar, wait 15 minutes, then recheck your blood sugar. If your blood sugar is still too low, you’ll consume another 15 g of sugar.
Use caution in a patient with a history of angioedema with another DPP-4 inhibitor because it is unknown whether such patients will be predisposed to angioedema with JANUVIA. Assess renal function prior to initiation of JANUVIA and periodically thereafter. The FDA website provides several useful tips on medication disposal. How long a medication remains good can depend on many factors, including how and where you store the medication. When you get Januvia from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. This date is typically one year from the date they dispensed the medication.
Medicines that interact with Januvia may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with Januvia. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed. Initial combination therapy or maintenance of combination therapy may not be appropriate for all patients. These management options are left to the discretion of the health care provider. A two-year carcinogenicity study was conducted in male and female rats given oral doses of sitagliptin of 50, 150, and 500 mg/kg/day.
It’s important to keep your type 2 diabetes well managed during pregnancy. Unmanaged diabetes can cause risks to both the mother and developing baby. These risks can include birth defects, high blood pressure, and miscarriage. It’s not known if Actos is safe to take during pregnancy. In animal studies, there were no birth defects noted in pregnant animals who were given high doses of Actos.
